Advancements in Gene Editing and Cell Therapy Research
Advancements in Gene Editing and Cell Therapy Research
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This document outlines the role of a Senior Research Associate in the Sail Immunology Platform, focusing on the innovative use of CD8-targeted LNPs for CAR-T therapy. It discusses the limitations of traditional CAR-T manufacturing, the objectives of assessing LNP delivery, and the methodologies employed, including flow cytometry and NHP studies. Results highlight CAR expression and B-cell depletion, emphasizing execution excellence and data integrity. The translation section connects findings...