Second-Line Diuretic Therapy in Ambulatory Chronic Heart Failure

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This presentation offers an in-depth exploration of managing ambulatory chronic heart failure, emphasising challenges such as diuretic resistance and its impact on patient outcomes. Key topics include the mechanisms of diuretic action, the principles of sequential nephron blockade, and data-driven insights into second-line therapies like metolazone. Practical strategies for safe implementation and monitoring, supported by findings from studies such as DEA-HF, highlight evidence-based...