Sepsis: From Historical Definitions to Personalized Therapy

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This lecture covers the historical evolution of sepsis, modern definitions and criteria, clinical guidelines, and current research in therapeutic approaches. Emphasizing sepsis pathophysiology, it explores inflammation, immune responses, and organ dysfunction. The session integrates the emergence of personalized medicine, highlighting biomarker-driven interventions, AI applications, and adaptive trials. Future perspectives center on unified protocols and innovative care models, presenting a...