sglt2 inhibitors-medicines history,mechanism of action,adverse effects,indications,latest research to support its use
sglt2 inhibitors-medicines history,mechanism of action,adverse effects,indications,latest research to support its use
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This overview explores SGLT2 inhibitors, tracing their development and clinical milestones while elucidating renal glucose reabsorption and natriuresis. It highlights the benefits and risks associated with these medications, including cardio-renal advantages and potential complications like infections and volume depletion. The latest evidence from key trials such as EMPA-KIDNEY and DAPA-CKD is reviewed, alongside emerging research in obesity and heart failure, providing essential insights for...