Broadening Horizons in CD3-Labeled Molecule Synthesis

This lecture provides an in-depth exploration of CD3-labeled molecules, focusing on their synthesis methods and mechanisms. It begins with an introduction to bioisosteric replacement and the significance of deuteration in pharmaceuticals. Key synthesis pathways, including C–CD3 bond formation and functionalization techniques, are discussed with real-world applications. Mechanisms such as reduction, catalytic cycles, and radical strategies are analyzed. The session concludes with innovations,...