Eplerenone in Cardiology: Beyond Mineralocorticoid Antagonism

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Explore the therapeutic potential of Eplerenone in this comprehensive lecture, drawing on its selective mineralocorticoid receptor antagonist (MRA) nature and favorable side-effect profile compared to spironolactone. Learn about its molecular structure, reduced risk of gynecomastia, and cardioprotective mechanisms that influence oxidative stress and heart failure management. Delve into its established role in HFrEF, uncertain efficacy in HFpEF, and comparisons with finerenone. Conclude with a...